 CLC bio have overcome the challenge to analyze Next Generation Sequencing data faster than it is produced, by implementing a SIMD-accelerated assembly algorithm in their Next Generation Sequencing solution, CLC Genomics Workbench - a cross-platform desktop application with a graphical user-interface.
CLC Genomics Workbench on Mac OS X platform CLC Genomics Workbench our new solution for analyzing and visualizing Next Generation Sequencing data. It incorporates cutting-edge technology and algorithms, while also supporting and integrating with the rest of your typical NGS workflow.
 CLC Genomics Workbench is available on Windows, Mac OS X, and Linux platforms.
Click here to see an overview of the features in CLC Genomics Workbench
A platform of solutionsCLC bio provides not only desktop based Next generation Sequencing analysis software, but a whole platform of Next Generation Sequencing solutions, ranging from High-performance computing and server solutions to databases and customized software solutions, adapted to your specific needs and workflows.
 Benchmarking with E. coli data
In benchmark tests we have assembled half a million 454 reads against the full E. coli reference genome in around 2 minutes on a dual-core laptop with 2 gigabyte RAM. This speed-up, based on integrated SIMD high-performance computing technology, increases even more when using a computer with more CPU-cores and RAM.
| A few benchmarks |
Time (minutes) |
| 454: Reference assembly and visualisation of 439,000 reads to E. coli (5 mega bases) on a 2GB ram, dual core 2.13 GHz, 32 bit laptop computer. |
2 |
| Solexa: Reference assembly and visualization of 2 x 2.7 = 5.4 million paired end reads (1 lane) to E. coli (5 Mega bases) 8GB ram, dual core 2.5 GHz, 64 bit desktop computer. |
7 |
Assemble genomes of any sizeCLC Genomics Workbench is very fast and allows you to do reference assembly of genomes of any size - the only limit is the amount of RAM on the machine running the software. Furthermore CLC Genomics Workbench also supports de novo assembly, SNP detection, and a large number of downstream analyses.
Director of Scientific Solutions at CLC bio, Dr. Roald Forsberg, PhD, states
We set out to overcome two major challenges when analyzing Next Generation Sequencing data. One was to eliminate the analysis bottleneck by being able to analyze NGS data faster than it is produced. We overcame that by implementing an accelerated assembly algorithm in CLC Genomics Workbench which preliminary benchmark tests confirm is a very fast assembly algorithm. Secondly, we wanted to deliver user-friendly software which makes powerful NGS analysis software available to all biomedical researchers.
454, SOLiD, Solexa - no problem!We support all the major Next Generation Sequencing platforms, such as SOLiD, 454, Solexa, Helicos, and of course also Sanger. We are working closely together with all the instrument vendors to ensure full integration in the ongoing development. |
